Balanced translocations have no apparent effect on an individual, as no genetic material is gained or lost.

However, as with all types of translocations, there is the chance that there is a gene or other functional part of the genome at the break point, and if this is disrupted it can have phenotypic implications.

. May 19, 2023 · Background Patients with balanced X-autosome translocations and premature ovarian insufficiency (POI) constitute an interesting paradigm to study the effect of chromosome repositioning.



We suggest that incomplete skewing of X inactivation (>97 %) of the daughter could justify the infertility. When balanced translocation occurs, a. Recurrent spontaneous abortion (RSA) is often idiopathic, but structural chromosomal abnormality is an important nosogenesis.


Preimplantation genetic testing for structural rearrangement (PGT-SR) has been widely implemented to improve the clinical outcomes by selecting euploid embryos for transfer. . .

. A balanced reciprocal translocation consists of reciprocal material exchange between two non-homologous chromosomes.

cc | Übersetzungen für 'balanced translocation' im Englisch-Deutsch-Wörterbuch, mit echten Sprachaufnahmen, Illustrationen, Beugungsformen,.


Although there is an equal theoretical. .

. Couples with balanced translocations have a 50% chance of having RPL and a 20% risk of having children with unbalanced chromosomal aberrations.

As deletions within Xq21 do not cause POI, and since.

. . Look up the English to German translation of balanced translocation in the PONS online dictionary.

3)] and one balanced double translocation [46,XX,t(1;21);t(7;16)(1p21; 21q11) (7q31;16q23)] inherited from the mother. We report rare familial unbalanced translocation of chromosomes 7 and 12, which was diagnosed prenatally at 20+3 weeks of gestation. 1 Carriers of a balanced chromosome aberration often experience multiple miscarriages of unbalanced products of conception and are therefore very anxious about taking any risk when their pregnancy. Use in clinical context. Dec 4, 2021 · Introduction De novo balanced reciprocal translocations mosaicism in fetus conceived using preimplantation genetic testing from a different balanced translocation carrier parent has been rarely reported. Rare Chromosome & Gene Disorder Guides.


. Usually, balanced reciprocal translocations can be diagnosed by karyotype analysis (an example of translocation name within a karyotype report could be: 46,XX,t (12:18) (p12;q12.

09, 04:42: A fair and balanced portrayal of someone.

Accurate breakpoint mapping in apparently balanced translocation families with discordant phenotypes using whole genome mate-pair sequencing.

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Balanced translocations have no apparent effect on an individual, as no genetic material is gained or lost.